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Their creative choices ultimately provide intrinsic meaning to the content, which can be individually inferred by the viewer's perception.
They are also often denoted as individually inferred haplotypes.
For these reasons we think it is worthwhile to have a closer look at haplotype uncertainty with special emphasis on misclassification probabilities of individually inferred haplotypes.
Hence, the half site specific adaptations inferred for the E153R substitutions (i.e., global topological alterations and possible modifications on the 5'-NN first basis step) are, in principle, permissive for the adaptation individually inferred due the simultaneous T147F and K160R substitutions (i.e., a GT- TT dinucleotide step substitution at the center of the half site).
Furthermore, if some haplotypes can be expected to be inferred correctly or with only small error with respect to sensitivity and specificity as in the example of the CAPN10 haplotype mentioned, analyses based on individually inferred haplotype are most powerful.
Individually inferred haplotypes, on the contrary, can easily be incorporated into generalized linear models (GLM), which provides wide flexibility in the modelling of underlying inheritance assumptions, the study type, the type of outcome variable and gene-environment interactions.
Similar(53)
We masked the anticodon triplet as 'NNN' in all tRNA genes, aligned all tRNA sequences from each species individually and inferred a maximum likelihood phylogenetic tree for each alignment.
LoFreq's approach of discriminating SNVs individually by inferring an error probability based on the quality score assigned to individual nucleotides clearly overcomes this problem, although at the expense of recall.
When inferring migration rates we divide the year in two, with constant migration rates inferred individually in each partition.
Secondary structure models are available for a large set of almost complete SSU and fragments of LSU in the SILVA database [ 56] but most variable regions of LSU remain to be inferred individually.
Maximum-likelihood (ML) phylogenetic trees were inferred individually for each gene cluster with RAxML 7.3.2 (Stamatakis 2006) using the best-fitting amino acid substitution model as determined by the RAxML amino acid substitution model selection Perl script.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com