Each reproductive trait measured was investigated individually for evidence of QTL in the genome.
Following regression, the Grambsh and Therneau test 11 was used to assess each variable individually for evidence of proportional hazards assumption violation.
None of the remaining 45 lincRNA loci individually exhibited evidence for a significantly elevated substitution rate above neutrality in comparisons of D. melanogaster with D. simulans and D. yakuba.
To test whether the traits considered in this study (intestinal length and volumetric plant-detrital proportions in diet) individually showed evidence of phylogenetic signal two metrics were utilised – the K statistic [ 61] and Pagel's λ[ 62].
Finally, our genome-wide MK analyses show that genes with individually significant evidence for recurrent adaptive protein evolution are overrepresented on the X chromosome and, separately, tend to be enriched for functions in reproductive biology and/or chromosome biology, suggestive of frequent genetic conflict (e.g., satellite DNA-binding proteins, nuclear pore proteins, kinetochore proteins).
With WebChoice patients can monitor their symptoms, obtain individually tailored, evidence-based self-management support, ask questions to a clinical nurse specialist, communicate with other patients in a Forum, and use a diary.
We observed partial protection of the guanosine at the 3' splice-site AG dinucleotide by PUF60 and U2AF65/35 when incubated individually, as evidenced by the decrease in cleavage product 2 (Figure 5C and 5D).
For example, information from individual case studies can be combined, so that even if they represent relatively weak evidence individually, the aggregated value is strong.
Together, these results show that the disease candidate loci studied here as a whole are evolving in a distinct manner from either the wood quality or drought tolerance candidate loci, with some disease candidate loci individually showing significant evidence for adaptive evolution.
Scope appears to exist for the exploration of further lines of supporting evidence individually and, perhaps, in combination.
