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For example, by aligning reads from DO mice to a single search space that includes individualized sequences of both alleles for every annotated isoform, our analysis approach provides direct estimates of allele-specific expression.
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We have constructed ESTcalc, an online webtool, which allows users to explore the results of this study by specifying individualized costs and sequencing characteristics.
We have also developed ESTcalc http://fgp.huck.psu.edu/NG_Sims/ngsim.pl, an online webtool, which allows users to explore the results of this study by specifying individualized costs and sequencing characteristics.
Her team plans next to use CRISPR to target individualized differences in the DNA sequences called single nucleotide polymorphisms (SNPs).
The highly individualized information provided from deep sequencing has the potential to find individualized biomarkers for treatment and disease monitoring [ 38, 39].
While existing databases may allow individualized searching by expression, keyword, or sequence criteria, it is the unification of these fields that makes angaGEDUCI a unique facilitator of experimental design.
The remaining variable genes are distributed throughout the H. pylori genome and some of them have been individualized in clusters of instability concerning blocks of 5 8 coding DNA sequences (CDSs).
The rapid breakthrough and development of microarray and sequencing technologies is probably the main tool for paving the way toward "individualized biomarker-driven cancer therapy" or "personalized medicine".
Using whole-genome assembly comparison (WGAC) and whole-genome shotgun sequence detection (WSSD) approaches by next generation sequencing (NGS), we probed formation signatures of both segmental duplications (SDs) and individualized CNVs in an integrated fashion, building the finest resolution CNV and SD maps of pigs so far.
By sequencing all these rearrangements and using alternate locations for consensus primers and, if necessary, even individualized TaqMan probes to cover cases with somatic mutations in the V-gene, it should be possible to attain a much higher feasibility rate.
It is individualized.
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