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These LOE-1 studies involved validation in both a multicenter randomized prospective clinical trial in which validation of the biomarkers was the primary aim of the trial and a pooled analysis of individualized data from both unpublished and published studies [ 7- 9].
To the best of our knowledge, uPA and PAI-1 are the first breast cancer biomarkers to have their prognostic and predictive utility validated in either a randomized prospective trial or a pooled analysis of individualized data from both published and unpublished data (that is, in two independent LOE-1 studies) [ 5, 6].
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No packets of concentrated, highly individualized data on our members and their lives.
We conducted a cross-sectional study using individualized data obtained from the SNHS done in 1987 , 1993 1995, 1997, 2001, 2003, and 2006.
At the moment, individualized data isn't that useful to marketers.
It collects individualized data, structures how the data are used to plan and evaluate a client's treatment, and produces aggregate information relevant for research and program purposes.
Creating individualized data collection systems can be time-consuming, and certainly cannot be expected of all teachers to do on their own.
Every day, clinicians are working to better coordinate care and mine healthcare information to make individualized, data-driven decisions for each patient based on their specific medical needs.
Third, we must ensure innovation in the classroom through the use of digital content and tools to provide individualized, data-based learning and improve educational outcomes.
The modeling system itself is comprised of two basic components: the modeling infrastructure (PyBioS) and the model itself – ModCell™ – which can be individualized with data from a single patient, and then explored, using the tools provided by PyBioS [ 85] to create the ModCell™ systems biology integrated platform (Fig. 2).
REST© software was used for comparison of qPCR data from individualized samples by randomization test as previously described (Pfaffl et al., 2002).
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