Sentence examples for individualized cell from inspiring English sources

But he said that in practice, therapeutic cloning would "never, ever fly" because it is individualized cell therapy, not mass production, that is needed for cell therapies to succeed commercially.

Although cellular immunotherapy based on autolgous dendritic cells (DCs) targeting antigens expressed by metastatic cancer has demonstrated clinical efficacy, the logistical challenges in generating an individualized cell product create an imperative to develop alternatives to DC-based cancer vaccines.

However that may be, conditionally immortalized CD40-stimulated B cells present new opportunities to study B cell function and differentiation, and they offer themselves as tools for individualized cell or gene banking and for use in cellular immunotherapy.

Individualized cell based subtelomeric profile will lead to design a reliable signature of subtelomeric p/q ratio for SCN and SI in BUC and ALN cells.

"Andy's work is among the first, if not the first, to really show that [tumors] don't need to individualize cells to undergo full metastasis," says Peter Friedl, a biologist at Radboud University in the Netherlands, whose movies of cancer cells in motion helped convince cancer biologists that collective invasion is important.

In conclusion, the immunophenotypic profiles determined by flow Cytometry using developmental antigens yield a better understanding of the complex biologic features of common ALL and improve the ability to further classify the disease and detect minimal residual disease, which together better characterize individualized leukemia cell populations.

Most approaches manufacture individualized CAR+T-cells from the recipient or HLA-compatible donor, which are revealing promising clinical results.

Over 99%% of the trichomes are at the mature stage, i.e. with four clearly individualized glandular cells (Fig.  3f, l, r and x).

Given the large number of RNA-Seq profiles in the public domain and our efforts to develop individualized T cell-mediated cancer vaccines, which require the knowledge of a patient HLA type and HLA expression to prioritize target epitopes [ 10- 12], we sought to develop an algorithm to utilize the sequence content of RNA-Seq reads to determine both HLA type and expression.

EMT which ultimately individualizes the cells, which then acquire a mesenchymal type, implies the loss of cell cell adhesion and cadherins and a switch of the cytoskeleton proteins from cytokeratins to vimentin [ 93, 152].

Consistent with this, our results show that End-1, an agonist of RhoA pathway, dramatically increases actin polymerization in CD34+RA cells and the cells exhibit individualized α-SMA and calponin filaments.