As the sequence composition of the individualised drug product will be patient-specific, formal preclinical toxicity studies are not feasible.
The entire process, from patient sample through individualised drug product back to the patient, has to be rapid, has to be robust and must comply with the regulatory requirements of a controlled drug development process defined by drug development guidelines.
"On the demand side, consumers are shifting away from mass production and increasingly seeking out individualised experiences and products.
Zak and Spector said they would like to retain some of its individualised experience when and if they explore selling products in physical locations.
Symptomatic treatment, such as mechanical compression, surgical haemostasis, fluid replacement and blood products, should be used in an individualised manner according to the nature and location of the bleeding.
Mann Deshi, for example, offers specially designed savings accounts, pension services and insurance products to its rural customers, as well as individualised loans.
Thus an individualised therapy may be associated with the use of a wide variety of products.
Thus, a personalised therapy concept that integrates individualised tumour genome sequencing and on-demand RNA vaccine manufacture to create customised drug products is both an exciting new therapeutic vision and is within our grasp (Kreiter et al, 2011b).
