Now, studies were designed to extend those earlier observations in order to better define the role of the individual subsets of DC during the pulmonary immune response.
RDC which have migrated to the MLN either constitutively from the normal (non-inflamed) lungs or in response to pulmonary inflammation/infection are believed to contribute to the DC population found in the MLN, but the contribution of the individual subsets of migrant RDC to the expanded population of DC found in the MLN following respiratory infection has not been clearly defined.
The average similarity values (Tables 3, 4) of the training set molecules towards individual subsets of actives and inactives of the training set, using three different fingerprints, suggest that the evaluation set compounds are more similar to inactives rather than actives within the training set, explaining the inferior performance of these methods when used individually.
Moreover it appears that the individual subsets of intestinal cDCs may play distinct roles in promoting different arms of the mucosal adaptive immune response.
The alternating optimization is an iterative procedure for minimizing the function f(X) = f X1, X2,.., X n ) jointly over all variables by alternating restricted minimizations over the individual subsets of variables X1, X2,…, X n [21, 22].
The individual subsets of cells that were previously defined were analyzed for BrdU+ (Fig. 5A).
Consideration of individual subsets of cooling towers with their dedicated cooling water operations yields suboptimal results.
Classification accuracy (CA) was used to evaluate the performances of the individual subsets and the integrations of the multiple subsets of each round of the analyses.
Next, cell-induced material deformations (i.e., displacements) are calculated using a recently developed digital volume correlation (DVC) algorithm that tracks the center displacement of individual spatial subsets of the recorded LSCM images in all three dimensions [28].
Following the sorting and culturing of 4 individual subsets, the only cell subset, which gave rise to adipose-derived and expanded-mesenchymal stem cells in our study, was originated from the conventional ADSCs subset.
