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Five configurations, characterised by individual sets of parameters, and presenting different fabrication cases, are proposed.
Taking into account the variation across individual sets of parameters and fit uncertainties (shown as bands in Fig. 6e), our data allow a separation of LII/III into three equally sized parts.
Using χ fits of sigmoids on the calculated MANOVA p values for the individual sets of parameters, we could determine the vertical depth at which the neuron populations within the sliding window became significantly different from the respective base window populations.
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For both Parts 1 and 2 of the methods, all simulations included 1,000 individuals each with an individual profile and individual set of PKPD parameters.
This repetitive approach was used to assess how the estimates of the parameter values change when considering a composite data set derived from individual sets of data.
To reproduce the irregularity of the individual oscillations a set of parameters controlling the individual patterns is drawn at random before each simulation.
Second, random sets of parameters are generated according to the designed probability distributions to formulate diverse individual LSSVR members.
Three different sets of parameters were used for the field model: one with basal ganglia parameters based on data from healthy individuals, one based on data from individuals with PD, and one purely thalamocortical model.
Two sets of parameters were used here.
In addition, for each individual, the most likely set of parameters that describe that individual was estimated, along with the patient's BCR-ABL1 response classification (slow vs. fast).
The legs are modeled with time-variant dampers, and the model is able to characterize the gait pattern of an individual using a minimal set of parameters.
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