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Considering patients harboring distant metastases, resistance and therapy failure inevitably occurs, in general over a time period of less than one year for each individual regimen [2].
It seemed that the eradication rate was associated independently with the different protocol and presence of ulcer scar.> Furthermore, Table 6 shows the cost of each individual regimen.
Future clinical management of patients with HAP and VAP may require patients to be stratified according to the antimicrobial resistance pattern of the bacterial species and pathogen density in order to select the optimal individual regimen.
Several anthracycline-containing regimens are currently used [ 15] and so far there is no direct comparison supporting superiority of an individual regimen provided that an adequate dose is used.
The regimen costs of therapy in each model stage are shown in table 2. These regimen costs are the weighted average of the daily costs of individual regimen components, shown in table 3, based on unit costs [ 20] and utilization in RESIST-2 (unpublished data).
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Individual regimens have been used in the patients presented.
Patients received treatment for an average of 9 months; no details about individual regimens were available.
The unit cost of individual regimens varied from a minimum of €552/month to a maximum of €1600/month.
Detailed analysis of the individual regimens, not included in this retrospective study, may help understanding of local differences.
12 19 Reassuringly, our results suggest that treatment was usually initiated on the day of diagnosis, although we were unable to comment on individual regimens.
These patients realize and understand the importance of the treatments in order to improve their condition and take their individual regimens very seriously.
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