On such an account, there is a ('mere') concept of refinement, abstracting away the idiosyncratic features of Peter's individual refinement, Paul's individual refinement, and so on.
The use of the identical spline representation for both sides permits a direct transfer of the necessary quantities, all the while still allowing an adjusted, individual refinement level for both sides.
But Ms. Fujimoto, drilling the Americans in endless variations on rudimentary folk or ritual songs, seemed to be striving for something more basic: not so much individual vocal refinement or panache as a unity of group spirit based on listening to one's fellow performers, a heightened sensitivity to musical surroundings.
AutoBuild [52] was used for iterative model building, and the resulting model subjected to 20 macro-cycles of combined TLS, occupancy, coordinate and individual ADP refinement in phenix.refine [53].
Such a plot would be an independent validation of the method by comparison to solution data, and it would also illustrate that the method goes beyond single conformer individual ADP refinement.
This process included rigid body refinement, individual and grouped B-factor refinement, and NCS averaging.
The models thus generated were refined with PHENIX using individual B-factor refinement (occupancies were not refined).
The model was refined using gradient minimization with weight optimization and maximum-likelihood targets, TLS refinement, and individual atomic B-factor refinement.
Successive positional and individual temperature factor refinements were alternated with manual model adjustment using TURBO-FROD O[66] and COOT [67] graphics.
Refinement in PHENIX included XYZ-coordinate refinement, real-space refinement, and refinement of individual anisotropic temperature factors.
