On such an account, there is a ('mere') concept of refinement, abstracting away the idiosyncratic features of Peter's individual refinement, Paul's individual refinement, and so on.
The use of the identical spline representation for both sides permits a direct transfer of the necessary quantities, all the while still allowing an adjusted, individual refinement level for both sides.
Leather, wood veneer, knurled gear shift, bottle cooler… scores of individual refinements that transport driver and passengers – wherever these fortunate few may be – to Crewe, England.
But Ms. Fujimoto, drilling the Americans in endless variations on rudimentary folk or ritual songs, seemed to be striving for something more basic: not so much individual vocal refinement or panache as a unity of group spirit based on listening to one's fellow performers, a heightened sensitivity to musical surroundings.
AutoBuild [52] was used for iterative model building, and the resulting model subjected to 20 macro-cycles of combined TLS, occupancy, coordinate and individual ADP refinement in phenix.refine [53].
Such a plot would be an independent validation of the method by comparison to solution data, and it would also illustrate that the method goes beyond single conformer individual ADP refinement.
The models thus generated were refined with PHENIX using individual B-factor refinement (occupancies were not refined).
Refinement consisted of rigid body, simulated annealing, positional and individual B-factor refinement with no sigma cutoff.
Cycles of rigid-body, individual-atom, and individual-B-factor refinement using Ramachandran and secondary structure restraints and optimized weights for stereochemistry and optimized atomic displacement parameters were carried out using Phenix (Adams et al., 2010).
The model was refined further using CNS Solve (version 1.1), including simulated annealing, gradient minimization, individual occupancy, and refinement of individual isotropic temperature factors.
The models were refined further using CNS Solve (version 1.1), by simulated annealing, gradient minimization, individual occupancy, and refinement of the individual isotropic temperature factors.
