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The individual prominence of each of these pathways in muscle wasting conditions is still debated.
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Similarly, the assignment of particular terms to individual prominences - or to two of the three prominences - highlights further pathways that may contribute to differential development (Figure 5).
In other instances, individual prominences are associated with specific developmental processes, and this is reflected by patterns of differential gene expression that give the prominences their unique identities.
The MdP and MxP also have a unique arrangement of genes that are either expressed at higher or lower levels in either of these individual prominences.
The final time point (E12.5) is when the individual prominences are about to initiate fusion to form the primary palate after which they cannot be distinguished as discrete entities (TS20.3).
In general, an increasing number of differences occurred between individual prominences at each successive time point consistent with a divergence of function accompanied by greater complexity of gene expression (Figure S2A).
And so a law school might hire an established scholar in international business law, or a recent United States Supreme Court clerk, in order to use that individual's prominence, prestige or affiliations to advance the law school's own academic reputation.
Quantitative RT-PCR (qRT-PCR) of individual facial prominences demonstrated that levels of SHH ligand expression varied in a prominence-specific manner.
The genome-wide analysis of transcripts present in the individual facial prominences yields a comprehensive overview of the similarities and differences in gene expression among the three facial prominences at five time points over a two day developmental window.
In a series of simulation experiments based on dynamic social networks, we test the prediction that social behaviors that help individuals reach prominence within their social group may conflict with their potential to benefit from their social environment.
For RNA-seq, individual facial prominences were harvested from control (n=8) and talpid (n=8) embryos at HH25.
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