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Individual methodological quality components for each study are reported in Table 1.
Table 2 displays the findings from the assessment of all 10 individual methodological quality items used.
An overview of how the individual methodological samples were handled is provided in Table S1 in Additional file 1.
Overall, the median number of individual methodological components assessed per systematic review was six (IQR 5 to 7), ranging from 1 to 27 items (table 2).
The individual methodological procedures of the evaluation were continuously developed during the study, according to the experience gained while working with the search engines.
Despite being labelled as the highest level of evidence (Level 1 and Level II evidence), these studies had low Cochrane reporting quality scores among individual methodological safeguards.
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The goal was to obtain as much data as possible, to avoid any bias that might be specific to an individual microarray methodological approach.
Consequently, it is generally recommended to assess study quality against individual relevant methodological criteria, depending on the context in which studies are conducted, however, always including criteria concerning the internal validity of studies (Jüni et al, 1999; 2001).
One important reason for such discrepancies is the relatively large number of individual and methodological errors in linguistic datasets 19; this is reflected by numerous cases of wrong translations, wrong homology assessments (incorrect identification of cognate words), and undetected cases of lateral transfer (borrowing) 17, 18.
Investigation of the roles of sex hormones in the development of PTSD and post-trauma sleep in trauma-exposed individuals entails methodological challenges (e.g., recruitment of recently traumatized individuals and measuring sex hormones and monitoring the menstrual cycle in the aftermath of trauma) and has not been conducted.
Generally, it is recommended to have at least one or two individuals with clinical expertise, and at least one or two individuals with methodological expertise in systematic reviews/meta-analyses and on the type of study designs you are including [ 19, 20].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com