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However, functional redundancy among localization elements has made the identification of individual localization factors difficult.
At the onset of our experiments we envisioned that individual phosphorylation events may control individual localization processes.
We represented the cluster of solutions by individual localization densities, defined as the probability of observing a specific eIF3 domain at a given point in space.
9 This (secretory phospholipase A2 family) enzyme plays a significant and varied role in many mammalian cells and the individual localization and function of the various sPLA2 members identified in skin (sPLA2-IB, -IIA, -IIC, -IID, -IIE, -IIF, -III, -V, -X and -XII) still must be defined.
Similar(56)
n = 353 single spots comprising 41,928 individual localizations.
a) BP-TRABI (black, n = 383 single spots comprising 40,091 individual localizations) versus TRABI (blue, n = 222 single spots comprising 18,232 individual localizations).
n = 383 single spots comprising 40,091 individual localizations for b)- e) Scale bar, a) 2 µm.
b) Classical biplane imaging (BP-FWHM, black, n = 353 single spots comprising 41,928 individual localizations) versus TRABI (blue).
Image volume is indicated and Z position of individual localizations is color-coded.
To determine individual plasmid localization, accumulated plasmid co-localization with Gcn5 and Sgf73, nuclear geometry, and anaphase duration; a Deltavision microscope was used (described above).
The data provided further evidence for the high anatomical variability of language areas, which underlined the relevance of an individual language localization and lateralization prior to brain surgery.
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