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Individual epidemics varied dramatically in size due to stochastic effects throughout the model.
However, the relative mortality of individual epidemics vary in different countries.
R can be determined in a straightforward manner for individual epidemics and is related to the circumstances, such as population vaccination status, under which the individual epidemics occur.
Our analysis indicated that several hundred cases were preventable during the 11-year period; however, among individual epidemics, a median of near 0 cases were prevented per 100,000 doses, and a maximum of 180 cases were prevented.
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Nonetheless, historical records can be of use in extracting defensible information pertaining to an individual epidemic's parameters, while not extrapolating to an etiologic conclusion.
Understanding the individual country epidemics, by means of collecting good quality surveillance data, is crucial to be able to provide the appropriate services and programs that are needed in these settings [ 76].
For both of these reasons, detailed spatial resolution is useful because aggregated datasets can obscure some of the factors that influence the timing and size of individual local epidemics.
Despite Severe Acute Respiratory Syndrome (SARS) and the 2009 pandemic influenza (pA/H1N1) focusing attention on vaccination and how best to protect individuals during epidemics and/or pandemics [ 5], the actual uptake rate of novel 2009 pA/H1N1 influenza vaccine was only 1.1% among the Hong Kong general public [ 6], while no data are available about the pA/H1N1 vaccination rate among children.
On the other hand, if we consider nonuniform transmission among individuals, the epidemic threshold increases, thus inhibiting the spreading process.
The implementation details of the base model are provided in supporting text (Appendix S1); model parameters, such as the full listing of contact probabilities, are given in the supporting information of a study by Germann et al. [2] The discrete-time simulation of infection events in individual-based epidemic models can be reduced to the generation of binomial deviates.
Influenza vaccines are the cornerstone of medical interventions aimed at protecting individuals against epidemic influenza.
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