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The device is based on micro-reservoirs etched into a silicon substrate that contain individual doses of drug.
All 21 subjects had motor fluctuations as defined by a history of marked fluctuations in motor symptoms in response to individual doses of PD medications, in spite of appropriate pharmacological adjustments.
By sequestering individual doses of chemical in stimuli-sensitive depot membranes and stacking them between stimulant barriers, automated pulsatile chemical release can be obtained from a simple polymer laminate.
During the course of the inquiry, investigators said they made numerous controlled purchases of heroin from the ring that totaled more than 5,400 individual doses of heroin, Addiction is what led many of the accused to join the operation, said the chief of department for the Nassau County police, Steven Skrynecki.
It was not powered to demonstrate superiority of the individual doses of lasmiditan to placebo (see Fig. 1).
Individual doses of IPTi are referred to as IPT-1, IPT-2, etc.
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The individual dose of each llama was determined prior to the injection according to its body mass.
In a subset of participants (N = 8) for which data was available, individual dose of methamphetamine (3 × 3 mg, IV) produced significant increases in positive subjective effects, and a preliminary analysis revealed that 3 mg rivastigmine was associated with reductions in these responses, as compared to placebo.
We waste the most resources when we pour a cold pot down the drain, while the individual dosing of Nespresso capsules reduces our consumption of the raw material to what will actually be put to use.
In two independent experiments, 10/10 of the animals passively immunized with an individual dose of 10 µl immune serum (diluted 1∶10 with sterile saline) survived, while 10/10 untreated control mice died (P: 0.01; Table 4, experiment 1).
The individual dose of PCB-153 at this mixture dose was approximately 254 μg/kg/day.
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