Sentence examples for individual disruption from inspiring English sources

Moreover, the individual disruption of Foxo1, Foxo3 and Foxo4 genes in mice results in different phenotypes [ 14, 16].

There are so many layers of redundancy and safeguards in place that individual disruptions of certain pathways may never cause disease on their own.

In addition, the fact that a double disruption of Rai1 and Dxo1, but not individual disruptions, is required for the accumulation of incompletely capped mRNAs during nonstress conditions indicates that the Rai1 and Dxo1 proteins function redundantly in the surveillance mechanism to detect and degrade incompletely capped transcripts.

The severity of several, but not all, EORTC QLQ C30 symptom items correlate strongly with the degree of individual circadian disruption.

This selection might have been based purely on selection for speedy replication; alternatively, the slowed replication might actually represent an average of individual replication-disruption events, each of which is counter-selected independently because genome integrity is selected.

However, the individual gene disruptions caused little or no effect on the in vitro survival of mutant parasites.

The expected fitness is calculated using the fitness of strains with individual gene disruptions, typically using a multiplicative model(wawb).

Characterization of the T-DNA insertion sites in cyp85A2-1 and cyp85A2-2 individuals confirmed disruption of this gene in these lines (Methods).

Notably, this method (Epistatic Miniarray Profiling- or E-Mapping), detects pairwise gene disruptions that cause the yeast to grow more slowly (negative epistasis) or more rapidly (positive epistasis) than the rate predicted using the individual gene disruptions.

By studying individual pathway disruptions, these pathways were shown to converge as patients progressed before treatment and to assume similar transcriptional profiles closer to the point at which they required treatment [ 105].

However the induced ablation of G9a in the background of Mili-deficiency in G9aCKO; MiliKO mice had profound consequences on the seminiferous tubules beyond those seen in the individual gene disruptions.