The non-canonical and canonical Wnt signaling pathways are indispensible for heart development [4], [5] and other biological processes including cell migration, cell proliferation, development [6], [7], and stem cell self-renewal [8], [9].
Furthermore, we found that HDAC activity was required for efficient DC differentiation and was indispensible for pDC development.
Taken together, Crx is indispensible for normal development of the visual system in humans and other mammals.
However, the mutant mice were viable and reached the adult stage without any gross developmental abnormalities, suggesting that Gpr97 is not indispensible for normal development.
Both the results above demonstrate that Sox2 is indispensible for early development, and blocking either maternal or zygotic Sox2 generates different effects on the differentiation of early embryonic cells.
The intercellular transport of ions and metabolites via an extensive network of gap junctions is indispensible for the growth, development, and proper maintenance of the mammalian avascular lens.
High-reactivity electrode materials are indispensible for developing high-performance electrochemical energy storage devices.
Hematopoietic transcription factor GATA1 is indispensible for the maturation of erythrocytes [ 60].
The only integrin subunits so far shown to be indispensible for appropriate mammary gland development are α2 and β1 [ 43, 44, 53].
First, IMC associated proteins, comprises alveolin proteins, a membrane occupation and recognition nexus protein (MORN), which associate with IMC and spindle poles and are indispensible for asexual and sexual development (Ferguson et al., 2008).
