It's not because I am indispensible, but because I can now see, when I look back, that like many of my hard working, compassionate colleagues, I was heading for burnout.
PCR has been indispensible for gene cloning because it can provide target gene fragments in vitro in large amount and short time without the limitation of restriction sites.
Because of its indispensible sterilizing activity, all new TB regimens in clinical development include PZA.
Because of its indispensible sterilizing activity, all new TB drug candidates in clinical trials are used together with PZA.
Contrastingly, the cell death shown here is completely at odds with this notion because caspases activation was indispensible for releasing the inflammatory materials.
Furthermore, because IRF-3/7 play an indispensible role for the induction of the optimal expression of type I IFNs, their delayed activation, relative to NFκB and AP-1, would likely postpone the onset of type I IFN-mediated innate antiviral responses, thereby greatly compromising the ability of the infected host to keep early viral replication in check.
It has been suggested that duplicated genes are mainly saved from removal through functional diversification, because of positive gene dosage effects, or because they are indispensible parts of a protein network, e.g. as subunits in an enzyme or signalling complex [ 102, 106- 110].
No, says Amazon, because this activity is not "integral and indispensible" to the job.
Composite materials are also becoming indispensible in modern industries such as aerospace, infrastructure, and energy because of their ability to customize the physical properties in addition to light weight, directional stiffness, and long fatigue life.
However, they are not truly restriction enzyme independent because DpnI digestion as positive selection for recombinant vector is indispensible in the reported PCRRC strategy.
