The loquacious monsters of his fiction remain vivid and indispensable voices in the raucous polyphony of a new age, an essential precursor to the breakthroughs of the imminent new century.
The latter is indispensable as a precursor for the major excitatory and inhibitory transmitters, glutamate and GABA (γ-aminobutyric acid).
CCR2 expression on DCs, or on DC precursors, is indispensable for proper Th1 responses (33, 34) and for the clearance of at least some intracellular pathogens in mice (33).
The amino acids through transamination and deamination actions might have supplied indispensable ketoacids to act as precursors for the maintenance of carbohydrate metabolism to meet the energy requirements during pollutant exposure [ 56].
Also, α-ketoglutarate can provide precursors for polyamine synthesis, indispensable for nucleotide synthesis.
The layer-by-layer assembly of three cycles of polyethylene glycol (PEG) and polyacrylic acid (PAA) around the rGO core was indispensable in achieving a chemically-modified rGO precursor that assembled with DOX to produce the spherical nanodrug.
Riboflavin is indispensable for cellular metabolism because it is the precursor of coenzymes flavin mononucleotide (FMN) and flavin adenie dinucleotide (FAD) (LeBlanc et al. 2011; Aller et al. 2014).
Polyunsaturated fatty acids (PUFAs) are essential dietary nutrients; they are indispensable as structural components of cell membranes and as precursors for eicosanoids, signalling molecules which act on reproduction and immunity.
We found many other insignificantly expressed transcripts in both the conditions (Additional file 4), which might bear an indispensable role in mosquito life cycle, e.g., vitellogenin, which is an abundant yolk precursor protein participating in egg maturation [ 75].
In this case essential metabolites cannot be derived from imported precursors, but rather need to be completely synthesized, making additional reactions indispensable.
