Steven Rattazzi is the indispensable heart of the piece, an actor who moves and speaks the text with charmingly nebbishy certainty.
They are the foundation, indispensable heart and essence of everything that appears on the stage; be it a play or a musical, whether in a school, community theatre, a church, or professional theatre in any town in America and also of course on Broadway (plus more than the 68 countries around the world that regularly produce and perform American theatre).
Free films, offered with a pre-screening glass of wine, include Carlos Saura's indispensable, heart-wrenching "Flamenco" on Feb. 21.
When the subject comes up, you might expect planners to say that the work they do makes them as indispensable as heart surgeons or the bomb squad.
NRG1, a member of the epidermal growth factor family, has been comprehensively documented as an essential paracrine regulator of cell cell communication through activation of its ERBB tyrosine kinase receptors, and is indispensable in heart development and adult cardiac physiology.
For example, AtPEI1, an embryo-specific CCCH gene that is indispensable for heart-stage embryo formation, was first isolated using a virtual subtraction method from the cDNA library of Arabidopsis embryos [ 8].
Genetic manipulations to disrupt Capns1 constitutively or conditionally in mice cause embryonic lethality and cardiac hypertrophy, respectively, indicating that calpains are indispensable both to heart-specific functions and to life itself.
Thus, the Hippo pathway is indispensable for regulating embryonic heart development and maintaining basal heart homeostasis.
Peter Preston, the editor during most of this period, and Ian, his managing editor, were the indispensable pair at the heart of the enterprise.
Ronald Grainger, who has died aged 91, played a major role in transforming radiology from a limited discipline, based largely on radiography (X-rays), into a vast and indispensable speciality at the heart of all medical clinical management.
In her lecture Violationism Or Sorcery In Science, she said: "to be an adept in [magic], it is indispensable to be pure of heart, clear of conscience, and just in action".
