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Furthermore, methods facilitating sensitive mixture detection and relative quantification of allele proportions are indispensable for the study of heteroplasmy, mitochondrial sequence evolution, and mitochondrial disorders.
Therefore, understanding how oncoprotein-oncoprotein interacts and how oncoproteins drive the cell division cycle is indispensable for the study of molecular oncology.
Sensitive methods for determining DNA adducts are indispensable for the study of chemical mutagenesis and carcinogenesis and for biomonitoring human exposure to genotoxic agents.
Animal models of SMA have been indispensable for the study of physiologic roles of SMN in muscle cells and neurons as well as for the dissection of pathological events leading to SMA.
Furthermore, it may even be amenable for large practical clinical trials in the community, which are indispensable for the study of the relative effectiveness and optimization of our current treatment option for this complex and dynamic disease.
Results Because it is not feasible to take biopsies of the nervous system from patients with DM1 for histological examinations, animal models are indispensable for the study of the mechanisms underlying respiratory failure in this disease.
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The current method provides an indispensable tool for the study of non-equilibrium gravitational system.
Over the last decade, conopeptides have proven indispensable reagents for the study of vertebrate neurotransmission.
Metabolomics is quickly becoming one of the indispensable methods for the study of systems biology, following genomics, transcriptomics, and proteomics.
A genome-scale metabolic model (GSMM) is an indispensable tool for the study of metabolism that adopts a systems biology approach to integrate data from genomics, transcriptomics, proteomics and metabolomics.
Although recent evidence suggest that daily sampling of volumes as high as 35 μl in mice subject to CLP do not affect mortality [ 16], the usage of rabbits remains indispensable for the present study where daily sampling of volumes as high as 5 ml is necessary to collect the necessary amount of PBMCs.
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