Sentence examples for indispensable for its function from inspiring English sources

The accessory domain is indispensable for its function where it participates in dimerization of MABP-1 and in erythromycin binding.

It contains a Dab-1-like PTB domain indispensable for its function.

Since non-polymerising FtsA mutants show a severe cell division defect, it was concluded that polymerisation of FtsA is indispensable for its function.

Additionally, it provides new hints for the elaboration of alternative models describing the molecular mechanism of EMCV IRES mediated translation, in the absence of eukaryotic elements that were considered indispensable for its function.

We thus hypothesize that PRL-3 localizing to cell cyto-membrane is indispensable for its function in cancer metastasis via participation in the signal transduction pathway on the inner side of the membrane.

Interestingly, mutation of the Cdc5 NLS (and disruption of nuclear import machinery) also altered localization of Cdc5 to the SPB and the bud neck, suggesting that nuclear translocation of Cdc5 is indispensable for its function, especially prerequisite for its proper localization to the SPB and the bud neck.

However, later studies revealed that in addition to the ITIM, the transmembrane (TM) domain of FcγRIIB is also indispensable for its inhibitory function.

A number of studies have indicated that the self-association of CD147 is indispensable for its biological functions, and it is also suggested that glycosylation plays important roles in the self-association of CD147 (Grass and Toole, 2015).

Site-directed mutagenesis experiments revealed that the cyclic structure formed by the disulfide bridge between Cys and Cys in human ChM-I is indispensable for its anti-angiogenic function.

These results along with the data from BMS experiments confirmed that IKKβ is critical for DSB repair and its kinase activity is indispensable for this function.

CD122 is indispensable for proper function of the IL-2r as it is critically involved in signal transduction with its cytoplasmic domain [ 16].