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Although the mechanisms have not yet been fully characterized, constitutive PI-3K/Akt signaling is believed to promote proliferation and increase cell survival, which is an indispensable event during the process of cancer development (Samuels and Ericson 2006).
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DNA fragmentation and Lamin B cleavage have previously been shown to occur independent of caspase activation [ 44, 45], whereas PARP cleavage has been regarded as a caspase-indispensable event.
Proper actin cytoskeleton architecture and dynamics are indispensable for events in the immunological response such as T cell migration, redistribution of T cell receptors, and interaction with antigen presenting cells.
The vertex is activated in a situation when an incidence moment value and a threshold value representing conditions indispensable for the event to occur are equal.
It is indispensable to the event.
Cleavage of signal peptides is (almost) an indispensable co-translational event during protein export to the periplasm and/or ER lumen in prokaryotic and eukaryotic cells, respectively (reviewed in reference [ 112]).
It is mediated by synaptic adhesion molecules, and is among the earliest and most indispensable of molecular events occurring during synaptogenesis.
The imputation of Védrine, the French schoolteachers, and thousands of other commentators is that various internal deficiencies have excluded Islam from this indispensable cultural and intellectual event, without which no culture can be considered modern.
The data are indispensable for studying eruptive events and volcano-tectonic processes.
SPATO (spatial, person, action/attribute, and temporal object) was designed to integrate the indispensable elements of history events such as space, person, action/attribute, and time.
The journals of Edmond and Jules Goncourt are an indispensable record of the events of the day, but the brothers omitted any mention of Courbet's paintings in their first Salon review, because his Realism—"matter glorified"—offended them.
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CEO of Professional Science Editing for Scientists @ prosciediting.com