As most tissues are traditionally FFPE, an AR is indispensable because of formalin's cross-linking drawbacks (Srinivasan et al, 2002).
Although we are working on ways to eliminate the use of this tool, for the moment, this initial step is still indispensable (because of a too high computational workload) to get the total number of sORFs down in a sensible way, based on the coding index.
Model customization is often indispensable because standardization of local practices is difficult and patient populations may differ [ 10- 12].
Another passenger, Jose Wee, 63, a candle manufacturer, said he now visited Basilan freely to sell his products — an indispensable item because of the frequent blackouts here.
But it remains for me London's most indispensable theatre because of its tenacious and single-minded belief that, whatever the interpretative skills of the director, designer, actor or sound engineer, in the beginning, and irreplaceably, is the dramatist's word. 1.
Many are now more or less indispensable, primarily because of their importance in tiny, high-powered and extremely durable magnets used in everything from iPhone components to the Pentagon's missile guidance and satellite communications systems.
According to one account, Acheson once said that Mr. Battle was indispensable because he had "nerves of steel, a sense of purpose and a Southern accent".
In many phylogenetic analyses, historical DNA has been indispensable because it provides samples of taxa that are difficult or impossible for a researcher to obtain otherwise, such as historical samples of extinct species or species occurring in diverse areas of the world (e.g., Tepe et al., 2011).
This skill is often overlooked by those who feel indispensable because there is a fear of someone else doing what you perceive as your job, role, or task.
Especially in children, early identification and rehabilitation of HL is indispensable because even mild changes in hearing abilities may impair auditory, linguistic, communication and learning skills with life-long consequences.
As David Buss points out, regardless of the technology used to get two people to that point, meeting in person is indispensable, because it's the only true measure of whether "the chemistry is there or not".
