However, these studies do not rule out the possibility that Ku and Sir4 could be interacting indirectly, bridged by another yeast protein.
Cables in cable-stayed bridges are susceptible to vibrations induced by wind, wind/rain and indirectly by bridge tower and deck vibrations.
This indicates that the phosphorylated MDC1 SDTD peptide does not interact with MRN indirectly by bridging contacts with MDC1.
Interestingly our analysis of directly or indirectly targeted bridges revealed that these proteins could play a role in predisposition to some diseases.
PS may also be recognized indirectly by bridging molecules, such as Gas6 and protein S through the TAM family of receptors (Tyro-3, Axl, and Mer) [ 26].
Finally, the overall capacity of the structure and the position of the dissipation zones, as forced in the capacity design, were verified, in order to validate indirectly the entire bridge design strategy that is currently adopted in seismic codes.
Previously, it had been reported that 6- phosphonodifluoromethyl -2-naphthoic acid binds to the protein-tyrosine phosphatase PTP1B with its 2-carboxyl group interacting only indirectly through a bridging water molecule.
Benzonase nuclease was added to the extract to remove the remaining DNA, thereby eliminating protein interactions mediated indirectly by DNA bridging.
The Ku complex becomes anchored at the break site and is then used as a docking point by DNA phosphokinases, which directly or indirectly create protein bridges to pull the two broken ends together, and finally re-join them by a DNA ligase [ 16, 18, 19].
The DLA factor is a function of span or first flexural natural frequency of the bridge, and indirectly incorporates the dynamic effects of moving vehicles in the design.
