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Nineteenth-century chemists had to infer the shapes of molecules from clever but indirect experimentation.
There will continue to be ideas and realities that irk residents, but this type of "indirect" experimentation is the only way to arrive at a sustainable solution.
In their paper [ 20], indirect experimentation using mutagenesis was done and no biochemical proof supporting such a conclusion was provided.
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The phenomenon of antagonistic stiffness has been successfully demonstrated by free vibration and indirect force control experimentation.
These direct and indirect effects can be evaluated only by using controlled experimentation [32], albeit with limitations.
Gene connections were created based on direct (physical) and indirect (functional) interactions derived from genomic context, high-throughput experimentation, coexpression and knowledge reported in literature.
The direct manipulation [48] of executable artifacts is not only a means of cost reduction (compared with the indirect manipulation), but finding representations suitable for direct manipulation is an enabler for experimentation and insights.
These hypotheses would benefit from further experimentation on individual genes and on the mechanism by which direct and indirect effects are manifested.
However, based on experimentation exclusively with a p110α reporter construct, the authors interpreted PI3K regulation by RHO family members as indirect (Yang et al., 2012).
Experimentation welcome.
How indirect!
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com