Sentence examples for indirect disruption from inspiring English sources

The cytotoxicity of [Gem+Clo+Ed] combination might be through direct or indirect disruption of the mitochondrial functions.

Our results indicate that the disruption of miR-199a-5p miR-199a-5p miR-199a-5pe acid or TG stimupregulations to the during deregulation of target expression and the indirect disruption of ER stress, and apoptosis progression.

As determined by Western blotting, there was no expression of p19Arf in late passages of Twt-III cells, indicating that an indirect disruption of the p53 signalling pathway had taken place, thereby supporting that these cells had been malignantly transformed, although through a different process compared to the other cell lines (data not shown).

Since this could indicate either loss of CGRP affinity, absence of receptor expression or severe indirect structural disruption of the receptor structure, these mutants were not analysed further in this study.

Armed conflicts are associated with direct consequences like deaths, diseases, stress, migration and environmental destruction; indirect socio-economic disruption in the form of institutional, infrastructural and human capital destruction; and opportunity costs like famine due to disruption of agriculture as well as poverty due to disruption of commerce and education [ 1].

They account for most of the economic impact of earthquakes, direct (for repair or replacement) or indirect (due to disruption of occupancy, as tenants are reluctant to use the building before all damage is repaired).

Thus, the role of RA on the activity over the HCNR 81675 might be indirect through the disruption of hindbrain signals and the synergistic effect of inhibiting RA and Fgf pathway at 5.5 hpf.

As an indirect result of disruption in the transcription factor NFXL1, the nfxl1 mutant incurs a 20% decrease of the cytosolic H2O2 in relative to the steady-state level [ 50].

We note that blood brain barrier alterations are found in tg SOD1-ALS mouse models and that indirect evidence of disruption, such as increased cerebrospinal fluid (CSF) albumin/plasma albumin ratios, has been documented in patients with ALS (Leonardi et al., 1984; Apostolski et al., 1991).

They omitted wider indirect costs of disruptions to the economy and the value of lives saved other work shows this is 83% of the benefits of fighting a pandemic.

In this case, the apparent loss of Fab-7 insulator activity would have to be an indirect consequence of disruptions in the functioning of the neighboring dCTCF-dependent insulators, Fab-6 and Fab-8.