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Various indicators of progression of chronic kidney disease (CKD) have been used as outcomes in clinical research studies.
In the present study, we show that declining GFR and worsening proteinuria, two of the cardinal laboratory indicators of progression towards end-stage kidney disease, were substantially attenuated by the administration of culture modified bone marrow derived cells in a widely used model of non-immune chronic kidney disease.
Both FoxP3 and Gata3 were accurate indicators of progression rates.
Conventional indicators of progression to a high-grade glioma include contrast enhancement and histopathology.
The results suggest that these three major AGEs may be early indicators of progression of important DN lesions.
However, significant improvements in bone mineral density and bone gap area at the fracture site (both indicators of progression towards healing) were reported.
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The secondary end points were indicators of progression-free survival (PFS), time to progression (TTP) and the efficacy analyses-objective response rate (ORR) (ORR=complete response rates+partial rates).
High calcium induces terminal differentiation of keratinocytes that is coincident with a more dramatic reduction of p21Cip1 [21], which can be used as an indicator of progression of keratinocytes toward terminal differentiation in this study.
We assessed the effect of diet on prostate and GU weights as an indicator of progression of prostate tumorigenesis.
Persistent expression of E6 and E7 could serve as an indicator of progression from intraepithelial neoplasia to invasive cancer 165– 165.
In particular, IGRA is reportedly more accurate in diagnosing LTBI and as an indicator of progression to active TB [ 12].
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