Sentence examples for indicators of functionality from inspiring English sources

We then examined separately their evolutionary selection (purifying or relaxed), mechanism of duplication (e.g., segmental versus tandem duplications), and their expression levels/patterns, which are all potential indicators of functionality and evolutionary history.

In the present study, we decided a priori to use the functional well being scale (FWB) (range: 0 28), the fatigue subscale (FS) (range: 0 52) and the FACT-F Trial Outcome Index (TOI) (range: 0 108) as indicators of functionality.

Most of these retrocopies exhibit yield indicators of functionality, such as 1) they were already reported as transcribed genomic regions; 2) they contain an annotated reference mRNA sequence; 3) they appear to be under purifying selection; and d) they are related to the X chromosome, as some migrate out and others into the X chromosome.

Nevertheless, the observation reported here that lncRNAs of known function do show these signals of selection (reduced diversity and divergence) that are comparable to PC loci suggests that these signals are indeed good indicators of functionality for at least some proportion of noncoding loci.

The problem statement is related to microeconomic models of dynamic optimization of a company's indicator of functionality development.

Evolutionary conservation of sequence information is considered a good indicator of functionality and is used in microRNA target prediction programs [34] to assign confidence levels.

The differential expression of HOXD-AS1 in NB patients and in differentiating NB cell line is an indicator of functionality of this lncRNA.

Rather, it has been suggested that a better indicator of functionality may be HDL quality [ 23, 24], which depends on its subpopulations' type (large versus small) and constituents, including PON1 activity [ 25, 26].

The strong positive correlation between joint amplitude and the SCIM scale and also the upper limb abduction shoulder subscore shows that this metric could be a good indicator of functionality.

DOI: http://dx.doi.org/10.7554/eLife.03528.002 Small open reading frames (smORFs) of fewer than 100 amino acids exist in eukaryotic genomes in hundreds of thousands, but their annotation has been hindered by their size: short sequences are unable to obtain the high conservation scores that are the accepted indicator of functionality (Ladoukakis et al., 2011).

Previous work has shown that self-report measures are poor indicators of this functionality when measured by strength [ 40], motion [ 40], or imaging [ 19].