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The loss of body weight can, often, be a sensitive indicator of toxicity after exposure to toxic substances [ 33, 34].
Weight loss in animals is often an indicator of toxicity, and the most radiosensitive organs for PRRT are the bone marrow and kidney [8, 28, 29].
The results indicated that all A. ostenfeldii cells in the blooms harbored the genetic capability of PST production, making the detection of sxtA4 a good indicator of toxicity.
We arranged Ki and EC50 values (a frequently used indicator of toxicity) of the seven heavy metals in increasing order and found that the sequences were in good agreement.
Body weight is often used as an indicator of toxicity in laboratory animals.
To further investigate the protective effects of SurR9-C84A, LDH release was evaluated as a second indicator of toxicity.
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Since our strategy is based on simplifying the complexity of the data using indices of pathway activity we first asked whether these were also effective indicators of toxicity response.
Biological indicators of toxicity or stress in maize seedlings were not observed in treatments with engineered hematite and ferrihydrite NPs.
We also analyzed some biochemical indicators of toxicity (alanine aminotransferase, aspartate aminotransferase, urea and creatinine levels) after prolonged administration of these compounds.
A number of parameters were examined in blood as indicators of toxicity, including δ-aminolevulinate dehydratase (δ-ALA-D), catalase, glutathione peroxidase (GPx), alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea, creatinine, TBARS, non-protein-SH, ascorbic acid and selenium.
The lower IC50 values and variability obtained for morphological parameters, along with EGFP reporting, highlight these endpoints as better indicators of toxicity than shear cell mortality.
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