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The probe B2M was a predominate indicator of the involvement of the MHC class I pathway although other probes involved in protein processing and peptide loading (i.e. PSMB6, PSMB7 and tapasin) were also up-regulated among carriers.
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As part of the preliminary assessment, we investigated indicators of the involvement of OSH professionals in the planning phase and in completing the checklist and checked for any difficulties encountered in completing the checklist (Table 5).
In addition to the challenge tests, several other markers are placed in group A because they are clear indicators of the involvement of the immune system and their clinical relevance in the general population has been established, and modulation in the relevant direction would, therefore, be considered a beneficial health effect.
Directionality is an indicator for the involvement of a neuron in motion processing.
Mercury level in RBC from cord blood appeared as the best potential indicator of this involvement, although relationships with the mother's diet and level of mercury in the placenta also appear useful.
Level of participation is an indicator of interest and involvement, and volunteer participation suggests an even greater level of commitment and ownership.
We suggest that the implication is that, for this sample, the number of met needs would be a direct indicator of family involvement, whereas the number of unmet needs could possibly reflect family disengagement.
In multiple case study 3 we additionally used input from a benchmarking process for healthcare developed by Van Hoorn et al (20), since this became available after study 2. This study emphasized the indicator development process, the involvement of internal stakeholders and the comparability of the results.
Myoclonic jerks are seen more often in cases of EV71 infection than during infections with other enteroviruses and could be an early indicator of neurologic involvement, particularly in the brainstem.
The barrier with modified spectral transparency which is in fact the only indicator of light involvement in cell signaling, should not come into direct contact with cells in order to prevent any changes in the chemical and/or surface properties of the environment.
We found the percentage of involved nodes to be the most directly useful indicator of nodal involvement, but this is limited to node-positive cases.
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