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Running a simple Probit model regressing this dependent variable on the same set of covariates and on the indicator of substantial ICT and management changes, we obtain a negative marginal effect of the latter of 6.8% points significant at a 5% level.
From our own perspective, a P-value <0.10 is considered significant in Q-test (Cochran, 1954) and a I value of at least 50% is taken as indicator of substantial heterogeneity of outcomes in I statistic (Higgins and Thompson, 2002).
21 An I of at least 50% together with different directions of effects (ie, some trials favoring active treatment and others favoring placebo with an absolute SMD of at least 0.3) was taken as an indicator of substantial heterogeneity.
An I value of >50% was considered an indicator of substantial heterogeneity (values of I equal to 25%, 50%, and 75% were deemed to represent low, moderate, and high heterogeneity, respectively).
The I statistic indicates the proportion of variability across studies not explained by chance alone and the I value of 50% or more was considered to be an indicator of substantial level of heterogeneity [ 12, 13].
Along with others, they propose that low PR status may serve as an indicator of substantial activation of the growth factor signalling cascade, leading to hormonal therapy resistance [ 37- 40].
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An alpha error p < 0.05 and/or I2 of at least 50% were taken as indicators of substantial heterogeneity of outcomes.
Beside the bleeding intensity, the following auxiliary parameters provide valuable information: Low hemoglobin values and ferritin values can be indicators of substantial menstrual blood loss, sometimes leading to adaptation and hence higher thresholds for the bleeding categories.
The abundance of phosphorus and potassium in mistletoe tissues is an indicator for substantial xylem phloem xylem cycling of these elements in trees.
This is an indicator of growing love.
Our results suggest that genetic erosion may not be detectable with these indicators in some cases of substantial, ecologically-relevant demographic decline.
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