Sentence examples for indicator of selection from inspiring English sources

No indicator of selection was significant in the study by Voight et al. [44], with peaks of marginal significance only at PSD3, a gene located 200 kb 3' to NAT2.

The ratio of the nonsynonymous to synonymous substitution rate is an indicator of selection.

Non-response and the levels of non-response have often been taken as an indicator of selection bias.

We therefore investigated whether selection affects X vs. autosomal DNA sequences differentially, again using Tajima's D as an indicator of selection.

Thus, changes in the prevalence of these alleles can be a sensitive indicator of selection of parasite populations by AL and ASAQ.

Particularly for closely related taxa, such as human and chimpanzee, dN/ dS can be misleading and is not an unadulterated indicator of selection.

One can heuristically predict the impact of gene mutations, such as nonsense mutations and frameshift indels, on the structure of the protein product using indicators of selection pressure such as dn/ds test.

Tajima's D compares the proportions of low- to medium-frequency alleles and is an indicator of directional selection when negative, and balancing selection when positive [ 40] (Tajima 1989).

The ratio of nonsynonymous substitutions per nonsynonymous site (d N) to synonymous substitutions per synonymous site (d S) can be used as an indicator of positive selection (ω > 1) and purifying selection (ω < 1).

An excess of non-synonymous substitutions (Ka/Ks > 1) is an indicator of positive selection, while an excess of synonymous substitutions (Ka/Ks < 1) indicates purifying selection imposed by functional constraints.

Conventional MDK tests such as those based on the α statistic are usually used to detect only positive selection (but note that a negative α is an indicator of purifying selection or of slightly deleterious mutations segregating in a population).