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Using immunohistochemistry, lungs of E16.5 and E18.5 wildtype and Creb1−/− mice were analysed for expression of these markers as an indicator of proximal epithelial differentiation.
In addition, N-acetyl-glucoseaminidase (NAG) excretion rate, an indicator of proximal tubular injury, was higher in the uraemic toxin-overloaded rats compared with the control rats [ 72].
Our previous work has linked this indicator of proximal airway inflammation and/or remodelling with WTC-LI. 1 Our new finding may show that BWT is related to early vascular changes.
The percent of LDH release is a measure of hypoxia-induced membrane injury and increased percent LDH release is an indicator of proximal tubular necrosis (that is, the higher the percent LDH, the higher the degree of proximal tubular membrane disruption).
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The prevalence of indicators of proximal tubulopathy was determined at drug discontinuation.
Indicators of proximal renal tubulopathy (fractional excretion of phosphorus and uric acid, urine protein, and glucose) were measured in a substudy.
We did not find a statistically significant effect of FTC/TDF on serum phosphorus levels or indicators of proximal tubulopathy after stratifying by the presence of detectable drug affirming the association.
After initial exploration of the data, I employed phylogenetic ANOVA [ 33] to test for consistent relationships between qualitative bony indicators of proximal and distal remex attachment on one hand, and aspect ratio and body mass on the other.
Urinary KIM-1, an indicator of renal proximal tube injury, has been shown to be elevated at an early stage of injury, and increased levels are sustained throughout the progression of cell injury to proliferation and regeneration [ 27].
An alternative is to use some proximal indicator of kinship.
Participants' maximum values were assumed to be the most proximal indicator of cholinesterase recovery.
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