Hence, the 11C]-MET uptake can be used as an indirect, yet useful, indicator of the proliferative state of a tumor at a given time in rodent models.
The frequency of CFU-F in sample is another common indicator of BM-MMSC proliferactivitytivity.
Here we evaluated neurosphere formation as an indicator of cell proliferative potential.
MAI is an indicator of tumour proliferative activity that represents the mitotic activity in a given area of the tumour.
Ca2+ storage in the ER is an essential indicator of the proliferative, metabolic, and apoptotic status of cells.
Since the activation of Akt promotes cell cycle progression by modulating the expression (Brennan et al, 1997; Muise-Helmericks et al, 1998) and stabilization of cyclin D1 (Graff et al, 2000) and the SPF is an indicator of the proliferative state of the cells, the negative association between pAkt and SPF was unexpected.
Based on some experimental and clinical findings, an increased level of PAI-1 could be involved in repair processes leading to modulation of local proteolytic potential, thereby governing cell migration, and therefore could be an indicator of ongoing proliferative tissue repair process and progression of atherosclerosis [ 31].
The numbers of neurospheres formed after 3 days in culture as well as their average diameter (both indicators of their proliferative capacity) were calculated using Leica IM50 software (Fig. 6).
In addition, ECM proteins, such as α-SMA and PCNA, have been regarded as appropriate indicators of mesangial proliferative glomerulonephritis, including diabetic nephropathy [ 35, 36].
We also examined the clonogenic potential of SCC-SP cells as an indicator of their individual proliferative capacity.
