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Tumour hypoxia has been shown to be an independent prognostic indicator of poor outcome in prostate, head and neck and cervical cancers.
Compared to patients without ND, a ≥2-point ND was associated with a 3-fold risk of death (odds ratio 3.120; 95% confidence interval 1.231-7.905; P <.0165) after adjusting for admission NIHSS score, serum glucose, and age.A ≥2-point ND is a sensitive indicator of poor outcome and in-hospital mortality.
A rise of HsTnI may be an indicator of poor outcome.
ALDH was used as an indicator of poor outcome in patients with breast cancer (Ginestier et al., 2007).
Delirium may be viewed as an indicator of poor outcome after surgery.
Lymph node KLK6 positivity was an indicator of poor outcome (hazard ratio 3.7).
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Conclusion These pilot data suggest that initial biochemical changes after injury may be an indicator of poor outcomes that are not mitigated by surgical stabilization alone.
IL-6 is a reliable marker of inflammatory cascade activation and is an indicator of poor outcomes [ 26], whereas MPO represents polymorphonuclear leukocyte accumulation [ 27].
Analysis of human pancreatic cancers is consistent with this hypothesis; 20 of 106 tumors show a down-regulation of LKB1 compared to normal ductal epithelium and, remarkably, low levels of LKB1 can act as an independent prognostic indicator of poor outcomes of resected pancreatic cancer.
Elevated CSF protein levels, hydrocephalus and brain infarction on MRI at ICU admission represent major indicators of poor outcome.
Neuropsychological measures are related to some of the best indicators of poor outcome for children with conduct symptoms, such as early onset, stability across time, hyperactive symptoms, and aggressiveness.
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