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ICU admission was considered as a separate indicator of illness severity in addition to the initial PIRO score because it also incorporates the patient's response to ED treatment.
An index of clinical morbidity was calculated by dividing the log-transformed lifetime number of mood episodes by the log-transformed years of illness, to create an indicator of illness severity.
An explanation for this finding might be that age by itself represents an indicator of illness severity that bundles factors such as illness duration and number of episodes which might be related to a decline in cognitive abilities.
A new study may have found the underlying cause: A specific indicator of illness, called C-reactive protein (CRP), is higher than normal in bullying victims, even when they get older.
Since healthy animals, especially nursing mothers, will occasionally forage during the day, daylight activity is not a reliable indicator of illness in raccoons.
Being interviewed at home can therefore be seen as a proxy indicator of illness severity.
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Prospective offspring studies make possible the mapping of changes in multilevel indicators of illness risk from pre-morbid states to prodromes and finally to illness onset.
This may be related to possible moderating variables such as subsyndromal symptom severity, indicators of illness burden, and basic neurocognitive functions not always being taken into account.
We examined gene expression (mRNA) and protein levels of candidate immune and neurotrophic markers in well-characterized offspring of bipolar parents in order to identify reliable indicators of illness risk status and the early clinical stages of illness development.
In the present study, we aimed to specifically investigate visual cognitive and visual affective ToM abilities in eBPs and to explore their relationship with basic neurocognitive functions, subsyndromal symptom severity, and indicators of illness burden.
In addition, we could only use the data included in the original trial database, and we could not subsequently capture other potentially important indicators of illness severity including those that might have helped with the discrimination of this new model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com