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This pattern indicates that isozyme diversity is not an accurate indicator of genomic diversity for phenotypic and ecological features important in insular radiations.
In this study we used 16S rRNA gene sequence similarity as a straightforward indicator of genomic relatedness/distance and found that the ability to identify TCS orthologues between genomes was dependent on relatedness (Fig. 3).
In addition, as an indicator of genomic rearrangements between MuERVs as well as in other parts of the genome, we examined a short stretch of sequences (4 bp to 12 bp) flanking each MuERV for a direct repeat.
Nucleotide word frequency is a finer indicator of genomic specificity [ 29].
Loss of heterozygosity (LOH) is an early indicator of genomic instability, which increases the risk of malignancy.
SCEs are the outcome of the repair of double strand breaks, and their accumulation is an early indicator of genomic instability [ 3].
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Recently, we showed that DOC causes aneuploidy and micronuclei formation, indicators of genomic instability, in colon epithelial cells (Payne et al. 2008, 2010a).
We assessed whether these indicators of genomic instability at chromosome location 3p14.2 were present at an early stage, when the oncogenic potential of HR HPV is not yet fully expressed.
Formation of MN serves an indicator of intrinsic genomic instability and exposure to genotoxic agents [1], [2].
GC content is an important indicator of the genomic composition including evolution, gene structure (intron size and number), gene regulation and stability of DNA [ 23].
GC content is an important indicator of the genomic composition including evolution, gene structure (intron size and number), gene regulation and stability of DNA [ 52].
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