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The mixture ratio used in our study was chosen to reflect the NOAELs of each chemical alone, judged in relation to the most sensitive indicator of disruption of male sexual development, increased NR.
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Russia, Greece, Israel and Australia caught fire after prolonged drought, another indicator of climate disruption.
Egg production was monitored during the exposure experiments because impaired reproduction is a critical indicator of endocrine disruption.
Thus, while EPEC infection of TC-7 polarized epithelial cells led to a gradual loss in transepithelial resistance (TER; a well-defined indicator of barrier disruption), a 1 2 h lag period consistently occurred with the tir mutant before it induced a rapid response (Fig. 1A).
Apart from TVBN, two indicators of protein disruption are loss of sulphydryl group and production of carbanyl group.
These effects were considered as indicators of endocrine disruption [179], but are most likely related to the observed energy depletion.
In addition, the loss of membrane permeability, release of 260 nm absorbing material, and leakage of K+ ions to the outside can be sensitive indicators of the disruption of membrane integrity (Cox et al. [2001]).
On the other side of the ledger, in the June 2002 edition of EHP Supplements, Bernard Weiss, a professor of environmental medicine and pediatrics at the University of Rochester, reviewed the existing literature on sexually dimorphic nonreproductive behaviors as indicators of endocrine disruption.
The rationale for this approach is that, being local indicators of structural disruption, dehydrons belong to a twilight zone between order and disorder that can be identified using a reliable sequence-based predictor of disorder propensity such as PONDR [ 13].
In rats, exposure to p, p′-DDE in utero and through lactation significantly decreased cauda epididymal sperm counts (Loeffler and Peterson, 1999) and affected anogenital distance and nipple retention, both accurate indicators of endocrine disruption (You et al., 1998; Loeffler and Peterson, 1999).
In our analysis we took blocked comments as an indicator of abuse and/or disruption.
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CEO of Professional Science Editing for Scientists @ prosciediting.com