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Sure indicator of despair.
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As part of an endless flood of post-mortem election analysis, journalists and researchers recently began noticing a striking correlation between high local rates of opioid overdose deaths (and other indicators of despair and poor health) and a shift in swing state voters from Barack Obama to Donald Trump.
Immobility is interpreted as an indicator of behavioural despair (Porsolt et al., 1977; Cryan et al., 2002) and in the Gsx rats time spent in this posture was decreased, indicating an anti-depressive effect of Gsx.
Linear mixed model analysis of Despair and Depression index scores showed almost no effects.
"The grocer of despair".
These are statements of despair".
Decades of despair disappeared.
Out of despair?
Landmark of Despair Q.
That is arguably a counsel of despair.
You're on the verge of despair.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com