Studies of cloned animals indicate that somatic cells reprogrammed to pluripotency variably display telomere elongation, a common indicator of cell "rejuvenation".
To detect mitochondrial membrane potential, an indicator of cell apoptosis, the JC-1 assay kit (GeneCopoeia) was used according to the manufacturer's instructions.
The bactericidal activity was examined with 2, 3, 5-triphenyl tetrazolium chloride (TTC), an indicator of cell viability.
To investigate differences between two iPS cell lines (fibroblast-iPSC and hASC-iPSC), and also the gold standard human embryonic stem cell, we looked at cell stiffness as a possible indicator of cell differentiation-potential differences.
Recent data suggest that as many as 50% of older adults may have hypertonic plasma, an indicator of cell dehydration that predicts a range of adverse outcomes.
Here, a cyclometalated iridium III) solvent complex [Ir pdz 2(H2O)2]+[OTf]− (IrC1) was designed and synthesized as a phosphorescent indicator of cell death.
It uses resazurin as color dye to measure the metabolic capacity of cells - an indicator of cell viability.
The biocompatibility of both AuNPs was assessed by a proliferation assay, using mitochondrial functional activity as an indicator of cell viability.
Enhanced REL is also an indicator of cell death induction (Vidal et al., 2007; Luo et al., 2010; Mur et al., 2012).
The level of p27 was used as an indicator of cell cycle progression [30], [31].
Which of these provides the most precise indicator of cell size may vary with cell type and also with the optical and electronic characteristics of the sorter.
