High expressions of HER1 or HER2 when coexpressed with high HER3 and HER4 strongly correlated (P<0.05) with good prognostic indicators of bladder cancer (early stage of tumour (Ta T1), low grade (Grade I/II) and papillary type of tumour).
Correlations between RON or MET expression and clinicopathologic indicators of bladder cancer, and the biological effects of RON expression on cancer cells were examined, where suitable, using analysis of variance, Fisher's exact test, or χ test.
In conclusion, our results have highlighted the potential clinical role of CTC detection as an indicator of advanced bladder cancer.
The clinical indicators suggestive of bladder trauma include suprapubic pain or tenderness, inability to void and low urine output.
It has been shown that overexpression of NPM in bladder cancer is independently associated with cancer recurrence and progression to more advanced stages, suggesting that NPM overexpression is an important prognostic indicator for bladder cancer recurrence (Tsui et al, 2004).
MMP1 urine concentrations may therefore be a useful prognostic indicator for bladder tumour progression.
Commercial available kit (Jiancheng Bioengineering Institute) was used to detect MPO, an indicator of neutrophil infiltration, in the bladder tissues according to the protocol provided by the manufacturer.
To test the implicit assumption that migration of radioactivity from liver, spleen and bone marrow to kidney and bladder is an indicator of gradual efflux of radioactivity from living or dead labelled cells, we examined the distribution of activity after injection of [Zr]oxinate4 and that of cells that had been killed/lysed after radiolabelling with Zr and In.
Then, according to our results, sFas continued to rise with the increase of the aggressiveness of bladder cancer, and it may be used as an indicator of the malignant degree of bladder cancer.
