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The gastrocnemius muscle has previously been demonstrated as a good indicator of alterations in the skeletal muscle of emphysemic hamsters [ 22], including those in lipid peroxidation [ 2].
The FA measure represents the relative degree of anisotropy or directionality at each voxel and is an unspecific indicator of alterations in white matter microstructure (Peled, Gudbjartsson, Westin, Kikinis, & Jolesz, 1998).
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Actually COND is a primary indicator of alteration in aquatic system and it depends on natural flooding, evaporation and pollution load.
We suggest that these observations could be sensitive indicators of alterations in renal physiology and the occurrence of ARF.
At large scales, one of the clearest and most informative indicators of alteration of state and characteristics of ecological systems is land-cover change.
The main challenges in defining and assessing hydrological alterations are: how to define a reference state (referencing); how to define criteria upon which to build mathematical indicators of alteration (measuring); and finally how to aggregate the indicators in a single evaluation index (valuing) that can serve as objective function in the optimization problem.
The indicators of alteration zone identified in wells of Pad D and Pad E are also illustrated in this figure.
These proteins may not be sensitive diagnosis biomarkers for DM; however, they may be indicators of alteration in glycemic control.
Given that proteins are the functional molecules in cells, investigating alterations in protein abundance is likely to be a more informative indicator of phenotype alterations.
In conclusion, hsCRP is an important indicator of immune alterations in the pathogenesis of schizophrenia and has potential to be developed into a sensitive marker for the acute agitation in schizophrenia.
Among the biological parameters assessing the innate immune system, mHLA-DR seems to be an effective indicator of immune alterations [4, 5].
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