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In this study, we investigated the pathogenesis of CT and the extent of neural damage caused by T. canis larvae by measuring levels of BI-associated indicator molecules of TGF-β1, S100B, GFAP, NF-L, tTG, AβPP, and tau as well as UPS function by assessing ubiquitin expression in infected mice brains.
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A reagent of known concentration is dripped (or titrated, to use the term of art) into the unknown solution in the presence of an appropriate indicator molecule (for example litmus, in the case of a reaction between an acid and an alkali).
We also used dihydroresorufin as an indicator molecule to report the reduction of Ru(NH3 63+. Figure SI-6 (Supporting Information) shows a series of fluorescence images recorded during the electrochemical reduction of 250 μM Ru(NH3 63+ in a separate FEEM experiment.
The PVC matrix prevents leaching out of the indicator molecules from the fingernail sensor toward such repeated use.
The inadequacies of current tumor marker panels have led to the exploration of alternative indicator molecules, among which proteins from the mucin and cadherin family have taken on a distinctive role.
Note that the 3-D reconstruction offers more information, including the depth and size of the tumor, and the possibility to determine the exact number of fluorophore indicator molecules (or released drug), allowing for quantitative molecular imaging.
The indicator molecules tested included Amo, morphine, and melatonine.
The occurrence of ion suppression effects was indicated by the reduction of indicator molecule-specific signal intensities.
In a further set of experiments, the impact of the indicator molecule chemistry on the relative ranking of the AOXs in terms of reducing potency was studied (Table 2).
The extent of inhibition of the oxidation of the indicator molecule was found to be dependent on the kind and amount of antioxidant added.
The decrease of the interfacial potential at the emitter electrode is indicated by the inhibition of the oxidation of an indicator molecule.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com