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In this context, it is of note that reduced vitellogenin levels can only be interpreted as indicator for endocrine activity, if there is no systemic toxicity [186].
This study supports initiatives to further investigate whether ERβ presence in breast cancer samples is an indicator for endocrine response.
To replicate the OCP usage model with an alternate indicator for endocrine effects, age at menarche was investigated (Table 4).
Indeed, estrogen-receptor (ER) expression is a vital indicator for endocrine therapy 3. Furthermore, advances in molecular biology have led to the development of a molecular target representative of the HER2 BC subtype.
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Cyclin E, an activator of CDK2, when ectopically over-expressed is able to abrogate the anti-proliferative actions of tamoxifen on breast cancer cells [ 9] and is also shown to be a good indicator for endocrine-therapy failure [ 43, 44].
As previously described by Dowsett et al (2005), this might be an indicator of endocrine resistance.
Egg production was monitored during the exposure experiments because impaired reproduction is a critical indicator of endocrine disruption.
These effects were considered as indicators of endocrine disruption [179], but are most likely related to the observed energy depletion.
Plasma metabolite levels are main indicators of endocrine status, including health status, and are potential predictors of performance.
Three-quarters have involved my specialty, endocrine surgery — surgery for endocrine organs such as the thyroid, the parathyroid, and the adrenal glands.
It concluded that the nation's safety system for endocrine disruptors is broken.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com