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Quantification of the immune response to childhood vaccine, while up to the present used sparingly, may represent an excellent indicator for developmental immunotoxicity when conducted under appropriate conditions.
The complex mixture of the treated waste water had no effect on D. rerio morphology and did not change its primary and secondary motor neurons (indicator for developmental neurotoxicity).
The complex substance mixture of the treated waste water from a ward located in a neurological hospital, which is specialized on epilepsy treatment, had neither toxic effects on D. rerio morphology nor on the development of the primary and secondary motor neurons (indicator for developmental neurotoxicity).
The data further showed that the developmental stage, at which substances were applied (undifferentiated ESCs vs. differentiating EBs), may affect the embryotoxic effects and that analysis of transcript levels of various lineage-specific genes may be a better indicator for developmental toxicity (Schmidt et al. 2001; reviewed in Rohwedel et al. 1999).
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Recent guidelines and quality-of-care indicators for developmental follow-up of preterm children now reflect an awareness of early medical, social and psychosocial risk identification and interventions during the first year of life [ 16, 17].
Additionally, policies in emerging nations are concerned with increasing the supply of energy, as energy consumption per capita has become one of the major indicators for the developmental progress of a country.
Parental concerns about their children's development can be used as an indicator of developmental risk.
In fact, gestational age has been considered as a better indicator of developmental and neurological maturity than birth weight [ 41].
We report interactions between test and grade as indicators of developmental (operationalized as grade) differences in Think3d! participation.
In addition, the sensorimotor indicators of developmental status measured by the Bayley Scales have been shown to be rather instable across situations (Attig et al. 2015) and infancy (McCall et al. 1977) and were hardly predictive for later cognitive functioning (e.g., Fagan and Singer 1983).
Given the known relationship between heme and lipid metabolism [6], [12], [67], [68], heme levels can serve as an indicator for energy resource and developmental progress.
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