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In the first edition, patient experiences were defined as a separate indicator domain.
Multivariate analysis of the process indicator domain showed that all these variables remained independently associated with outcome.
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The conceptual framework was developed based on a systematic literature review of existing performance measurement systems, extensive consultations with (inter)national health care system experts and academics, conceptual analysis of the indicator domains (indicated in the matrix of Figure 1), and discussions with the MoH.
A total of 10 indicator domains describe the nature of worry or concern of nurses.
Variable incidences and combinations of indicator domains scored are encountered among deteriorating patients in general wards.
Fifth, the choice of relevant indicator domains should not be avoided because of a lack of available data.
Second-generation HCQIs, developed in 2013, introduced several refinements to the indicators, including more sophisticated risk adjustment strategies and additional indicator domains [ 5].
The proposed model can also explain why the epigenetic barrier established on the L1-rich EtoL pluripotency "indicator" domains is very stable.
It is largely unknown what mechanism drives replication timing changes during loss of pluripotency and exactly what forces the pluripotency "indicator" domains to replicate early in ESCs.
The majority of pluripotency "indicator" domains are likely to remain silent in most cancers, except for embryonal carcinomas and teratocarcinomas, whereas lineage-dependent EtoL domains might be commonly implicated in malignant dedifferentiation.
An initial version of the conceptual framework was based on the Lalonde model and the balanced score card [ 15]; many of the indicator domains and definitions of that model are still used in the DHCPR nowadays.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com