Disappearance of focal lesions, decrease in their size and/or number and return from focal or diffuse patterns to a normal bone marrow appearance are indicative of response.
Analysis of gene expression profiles revealed significant findings; please see Table S1: Down-regulation of IL15, NOS2A, CCR4 and up-regulation of IL17, CYP7A1, SELE, IL5, RPL3L genes in both patient categories indicative of response to p-H1N1-09 p-H1N1-09 p-H1N1-09
Expression of DNA repair and ROS detoxification enzymes may be indicative of response to increased respiration.
On the go/no-go task, the rate of commission errors is considered indicative of response inhibition.
They chose 24 patients to identify a methylation signature indicative of response and found nine probes that showed significant differences.
Clinical parameters indicative of response to VEGF-targeted treatments may help to limit patients' exposure to the drug in the absence of benefit.
Data on the expected magnitude of change in ADC indicative of response to standard therapy are becoming available for rectal, liver, lung and ovary tumours.
A proportion of patients did have changes in signal characteristics that may be indicative of response, such as focal non-enhancing areas that demonstrate increased T2 signal in keeping with necrosis and decreased enhancement and T2 signal suggestive of fibrosis.
An additional aim of the current research was to evaluate if this method presents a feasible means of determining hemodynamic biomarker profiles indicative of response to anti-angiogenic therapies in CRLM.
Cancers can also be divided into clinically meaningful subtypes based on their gene expression patterns that may be indicative of response to a treatment, like Her2 positive breast cancers [ 4] or KIT positive gastro-intestinal tumours [ 5], for example.
The corresponding images at day 85 show enhancement in the same span from the nipple to the chestwall but at a reduced level, indicative of response at this intermediate point during treatment.
