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There is a general toxicity test agreement that LC50 above 100 μgmL-1 is non-toxic while that below 100 μgmL-1 is indicative of toxicity.
No overt in-life or post-mortem indications of systemic toxicity, nor RNA and histological end-points indicative of toxicity attributable to inhibition of Notch signaling were observed at any dose tested.
The biomarkers used as indicative of toxicity were: cell density, cell viability, cell size, cell complexity, autofluorescence of chlorophyll a, active chlorophyll, effective quantum yield of PII (photosystem II) and reactive oxygen species (ROS).
Measures of cell death during this specific induction process are indicative of toxicity of the chemical compounds used.
This also highlights that mammalian toxicity studies are not necessary indicative of toxicity in avian species.
The highest achieved 25(OH D level in the VITD group was 64 ng/ml and far away from levels thought to be indicative of toxicity (>200 ng/ml) [ 22].
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Most patients, who developed serotonergic toxicity during ICU admission, were on antidepressant therapy and developed symptoms indicative of serotonergic toxicity after administering additional serotonergic drugs in the ICU.
This will allow us to assess whether gene expression changes are already indicative of toxic liabilities when standard parameters do not yet detect toxicity.
It was a severe norm violation, usually indicative of some toxicity or moral perversion.
We found that mice injected with Ad[CgA-E1A] had significantly elevated serum levels of ALT, which is indicative of liver toxicity, while no mice injected with Ad[CgA-E1A-miR122] Ad[CgA-E1A-miR122] Ad[CgA-E1A-miR122]
The eyes had a greater degree of external disorganisation and extensive patches of depigmentation indicative of increased toxicity (Fig. 6; depigmented areas marked by dashed lines).
More suggestions(15)
indicative of impairment
indicative of effectiveness
index of toxicity
evidence of toxicity
reflective of toxicity
indicative of intoxication
indicative of concentration
indicative of exposure
indicative of harm
indication of toxicity
test of toxicity
indicative of dose
indicative of illness
signal of toxicity
sign of toxicity
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